We are now welcoming participants from Scotland.

We are excited to be working with researchers from the University of Edinburgh, led by Professor Andrew McIntosh.

To sign up for the GLAD Study, click here.

About the GLAD Study

The Genetic Links to Anxiety and Depression (GLAD) Study is a research project which aims to explore genetic and environmental risk factors for depression and anxiety. It is led by the National Institute for Health Research (NIHR) Mental Health BioResource and researchers at King’s College London. This is the largest such study and following a successful campaign in England where over 20,000 people joined the study in less than four months, we are now expanding throughout the United Kingdom. We will be doing this in collaboration with researchers at Ulster University, University of Edinburgh, and Cardiff University. This innovative project will greatly add to our knowledge about depression and anxiety and provide valuable information to help improve treatments.

Depression and anxiety are the most common mental health disorders worldwide. In the UK, 1 in 3 people will experience symptoms during their lifetime. The GLAD Study aims to better understand depression and anxiety in order to find effective treatments and improve the lives of people experiencing these disorders.

To take part in the GLAD study, you must:

  • Have experienced clinical anxiety and/or depression during your life
  • Be aged 16 or over
  • Live in the UK

There are 4 simple steps to signing up to the GLAD Study:

  1. Register for the website and read the information sheet
  2. Provide consent
  3. Complete a ~30 minute questionnaire to see if you are eligible
  4. Send a saliva DNA sample through the post

Samples collected from Scotland will be stored through the NIHR BioResource research tissue bank in the NIHR National Biosample Centre in Milton Keynes, as well as the Wellcome Trust Clinical Research Facility in Edinburgh.

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Professor Andrew McIntosh

Andrew is the Principal Investigator in Scotland. He is a Professor of Psychiatry at the Division of Psychiatry, Centre for Clinical Brain Sciences at the University of Edinburgh. He leads the Generation Scotland Expert Working Group for Psychiatric Disorders and co-chairs the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC).


Professor Daniel Smith

Daniel is a professor of psychiatry at the University of Glasgow. He also works as a consultant psychiatrist with a special interest in mood disorders, particularly bipolar disorder. His research activity covers a broad area, from genetic epidemiology to stratified medicine and the development and testing of complex interventions.
More about Daniel


Dr Donald Lyall

Donald is a lecturer in Public Health at the Institute of Health and Wellbeing, University of Glasgow. He is an epidemiologist, and his research aims to understand how genetic and environmental factors, and their interaction, contribute to better or worse brain health.
More about Donald